diff --git a/CHANGELOG.txt b/CHANGELOG.txt
index ff34558305..8ab3f5bd86 100644
--- a/CHANGELOG.txt
+++ b/CHANGELOG.txt
@@ -49,6 +49,7 @@ Changelog
  * Maintenance: Remove unused Rangy JS library (LB (Ben) Johnston)
  * Maintenance: Update `PreviewController` usage to leverage Stimulus actions instead of calling `preventDefault` manually (Ayaan Qadri)
  * Maintenance: Various performance optimizations to page publishing (Jake Howard)
+ * Maintenance: Remove unnecessary DOM canvas.toBlob polyfill (LB (Ben) Johnston)
 
 
 6.3.1 (19.11.2024)
diff --git a/docs/releases/6.4.md b/docs/releases/6.4.md
index 69bf3398d7..2001b88c9c 100644
--- a/docs/releases/6.4.md
+++ b/docs/releases/6.4.md
@@ -68,6 +68,7 @@ depth: 1
  * Remove unused Rangy JS library (LB (Ben) Johnston)
  * Update `PreviewController` usage to leverage Stimulus actions instead of calling `preventDefault` manually (Ayaan Qadri)
  * Various performance optimizations to page publishing (Jake Howard)
+ * Remove unnecessary DOM canvas.toBlob polyfill (LB (Ben) Johnston)
 
 
 ## Upgrade considerations - changes affecting all projects
diff --git a/wagtail/images/static_src/wagtailimages/js/vendor/canvas-to-blob.min.js b/wagtail/images/static_src/wagtailimages/js/vendor/canvas-to-blob.min.js
deleted file mode 100644
index dd95826c95..0000000000
--- a/wagtail/images/static_src/wagtailimages/js/vendor/canvas-to-blob.min.js
+++ /dev/null
@@ -1 +0,0 @@
-!function(a){"use strict";var b=a.HTMLCanvasElement&&a.HTMLCanvasElement.prototype,c=a.Blob&&function(){try{return Boolean(new Blob)}catch(a){return!1}}(),d=c&&a.Uint8Array&&function(){try{return 100===new Blob([new Uint8Array(100)]).size}catch(a){return!1}}(),e=a.BlobBuilder||a.WebKitBlobBuilder||a.MozBlobBuilder||a.MSBlobBuilder,f=(c||e)&&a.atob&&a.ArrayBuffer&&a.Uint8Array&&function(a){var b,f,g,h,i,j;for(b=a.split(",")[0].indexOf("base64")>=0?atob(a.split(",")[1]):decodeURIComponent(a.split(",")[1]),f=new ArrayBuffer(b.length),g=new Uint8Array(f),h=0;h<b.length;h+=1)g[h]=b.charCodeAt(h);return i=a.split(",")[0].split(":")[1].split(";")[0],c?new Blob([d?g:f],{type:i}):(j=new e,j.append(f),j.getBlob(i))};a.HTMLCanvasElement&&!b.toBlob&&(b.mozGetAsFile?b.toBlob=function(a,c,d){d&&b.toDataURL&&f?a(f(this.toDataURL(c,d))):a(this.mozGetAsFile("blob",c))}:b.toDataURL&&f&&(b.toBlob=function(a,b,c){a(f(this.toDataURL(b,c)))})),"function"==typeof define&&define.amd?define(function(){return f}):a.dataURLtoBlob=f}(this);
\ No newline at end of file
diff --git a/wagtail/images/static_src/wagtailimages/js/vendor/jquery.fileupload-image.js b/wagtail/images/static_src/wagtailimages/js/vendor/jquery.fileupload-image.js
index 164a1cbbfc..00c4c58b08 100644
--- a/wagtail/images/static_src/wagtailimages/js/vendor/jquery.fileupload-image.js
+++ b/wagtail/images/static_src/wagtailimages/js/vendor/jquery.fileupload-image.js
@@ -22,7 +22,6 @@
             'load-image-meta',
             'load-image-exif',
             'load-image-ios',
-            'canvas-to-blob',
             './jquery.fileupload-process'
         ], factory);
     } else {
diff --git a/wagtail/images/templates/wagtailimages/multiple/add.html b/wagtail/images/templates/wagtailimages/multiple/add.html
index fa2cda64ef..0fb1c6574c 100644
--- a/wagtail/images/templates/wagtailimages/multiple/add.html
+++ b/wagtail/images/templates/wagtailimages/multiple/add.html
@@ -89,7 +89,6 @@
 
     <!-- this exact order of plugins is vital -->
     <script src="{% versioned_static 'wagtailimages/js/vendor/load-image.min.js' %}"></script>
-    <script src="{% versioned_static 'wagtailimages/js/vendor/canvas-to-blob.min.js' %}"></script>
     <script src="{% versioned_static 'wagtailadmin/js/vendor/jquery.iframe-transport.js' %}"></script>
     <script src="{% versioned_static 'wagtailadmin/js/vendor/jquery.fileupload.js' %}"></script>
     <script src="{% versioned_static 'wagtailadmin/js/vendor/jquery.fileupload-process.js' %}"></script>