diff --git a/Lib/wsgiref/simple_server.py b/Lib/wsgiref/simple_server.py
index 93d01a863ad..a0f2397fcf0 100644
--- a/Lib/wsgiref/simple_server.py
+++ b/Lib/wsgiref/simple_server.py
@@ -84,10 +84,6 @@ class WSGIRequestHandler(BaseHTTPRequestHandler):
 
         env['PATH_INFO'] = urllib.parse.unquote(path, 'iso-8859-1')
         env['QUERY_STRING'] = query
-
-        host = self.address_string()
-        if host != self.client_address[0]:
-            env['REMOTE_HOST'] = host
         env['REMOTE_ADDR'] = self.client_address[0]
 
         if self.headers.get('content-type') is None:
diff --git a/Misc/NEWS.d/next/Library/2023-10-29-03-46-27.gh-issue-66425.FWTdDo.rst b/Misc/NEWS.d/next/Library/2023-10-29-03-46-27.gh-issue-66425.FWTdDo.rst
new file mode 100644
index 00000000000..e7ede35891f
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2023-10-29-03-46-27.gh-issue-66425.FWTdDo.rst
@@ -0,0 +1,3 @@
+Remove the code to set the REMOTE_HOST header from wsgiref module,
+as it is unreachable. This header is used for performance reasons,
+which is not necessary in the wsgiref module.