diff --git a/Lib/test/test_httpservers.py b/Lib/test/test_httpservers.py
index 7c0edfea4f9..1c370dcafa9 100644
--- a/Lib/test/test_httpservers.py
+++ b/Lib/test/test_httpservers.py
@@ -815,6 +815,9 @@ class CGIHTTPServerTestCase(BaseTestCase):
             os.rmdir(self.cgi_dir_in_sub_dir)
             os.rmdir(self.sub_dir_2)
             os.rmdir(self.sub_dir_1)
+            # The 'gmon.out' file can be written in the current working
+            # directory if C-level code profiling with gprof is enabled.
+            os_helper.unlink(os.path.join(self.parent_dir, 'gmon.out'))
             os.rmdir(self.parent_dir)
         finally:
             BaseTestCase.tearDown(self)